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ascR [2017-12-11 12:21:25]
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ascR [2017-12-11 12:21:25]

alkyl-sulphur catabolism regulator, transcriptional activator of the snaA-tcyJ-tcyK-tcyL-tcyM-tcyN-cmoO-cmoI-cmoJ-ribR-sndA-ytnM operon
locus
BSU29400
pI
6.23
mw
35.08 kDa
protein length
308 aa Sequence Blast
gene length
924 bp Sequence Blast
function
regulation of sulphur metabolism
product
alkyl-sulphur catabolism regulator, transcriptional activator (LysR family)
essential
no
synonyms
ytlI
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.9|Biosynthesis/ acquisition of cysteine]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.4|Sulfur metabolism] → [category|SW 2.6.4.1|Conversion of S-methyl cysteine to cysteine]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]

    • Gene

    Coordinates
    3,008,938 → 3,009,864

    The protein

    Protein family

  • [SW|LysR family]

    • Expression and Regulation

    Operons

    genes
    [gene|741156D495BE3857683C8A0390764EAD83845ABC|ascR]
    description
    [Pubmed|9387221]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|16109943], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|50930C56C27D22715620A350220E3C56ADB41020|CymR]: repression, [Pubmed|16109943], in [regulon|50930C56C27D22715620A350220E3C56ADB41020|CymR regulon]

    • regulation

  • repressed in the presence of cysteine ([protein|search|CymR]) [Pubmed|16109943]
    • view in new tab

    Biological materials

    Mutant

  • MGNA-A169 (ytlI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/169 NBRP B. subtilis, Japan]
  • BKE29400 (Δ[gene|741156D495BE3857683C8A0390764EAD83845ABC|ascR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE29400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGTGCTCCCTCCTGTTT, downstream forward: _UP4_TAACTGAAAAAATAAAAACC
  • BKK29400 (Δ[gene|741156D495BE3857683C8A0390764EAD83845ABC|ascR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK29400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGTGCTCCCTCCTGTTT, downstream forward: _UP4_TAACTGAAAAAATAAAAACC

    • References

  • 15937167,11390694,16109943,16513748,9387221,16109943,23944997